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Takahira, Yusuke; Chen, Miao; Kawamata, Yu; Mykhailiuk, Pavel; Nakamura, Hugh; Peters, Byron K.; Reisberg, Solomon H.; Li, Chao; Chen, Longrui; Hoshikawa, Tamaki; et al (, Synlett)A simple and robust method for electrochemical alkyl C–H fluorination is presented. Using a simple nitrate additive, a widely available fluorine source (Selectfluor), and carbon-based electrodes, a wide variety of activated and unactivated C–H bonds are converted into their C–F congeners. The scalability of the reaction is also demonstrated with a 100 gram preparation of fluorovaline.more » « less
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Xiang, Jinbao; Shang, Ming; Kawamata, Yu; Lundberg, Helena; Reisberg, Solomon H.; Chen, Miao; Mykhailiuk, Pavel; Beutner, Gregory; Collins, Michael R.; Davies, Alyn; et al (, Nature)
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